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Mannan-induced Nos2 in macrophages enhances IL-17–driven psoriatic arthritis by innate lymphocytes

Previous identification of the inducible nitric oxide synthase (NOS2) gene as a risk allele for psoriasis (Ps) and psoriatic arthritis (PsA) suggests a possible pathogenic role of nitric oxide (NO). Using a mouse model of mannan-induced Ps and PsA (MIP), where macrophages play a regulatory role by r...

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Detalles Bibliográficos
Autores principales:	Zhong, Jianghong, Scholz, Tatjana, Yau, Anthony C. Y., Guerard, Simon, Hüffmeier, Ulrike, Burkhardt, Harald, Holmdahl, Rikard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955621/ https://www.ncbi.nlm.nih.gov/pubmed/29774240 http://dx.doi.org/10.1126/sciadv.aas9864

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