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Development of a new diet-induced obesity (DIO) model using Wistar lean rats

Obesity is an increasingly severe socioeconomic health issue worldwide. Rodents with diet-induced obesity (DIO) are widely used as models of obesity. The main aim of this study was to establish a DIO model using Wistar lean (+/+ or +/−) rats by feeding a high-fat diet (45 kcal% fat) to dams during t...

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Detalles Bibliográficos
Autores principales: Kimura, Yoriko, Yamada, Atsushi, Takabayashi, Yoko, Tsubota, Tsunehiko, Kasuga, Hisao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955747/
https://www.ncbi.nlm.nih.gov/pubmed/29151452
http://dx.doi.org/10.1538/expanim.17-0079