Deletion of both p62 and Nrf2 spontaneously results in the development of nonalcoholic steatohepatitis

Nonalcoholic steatohepatitis (NASH) is one of the leading causes of chronic liver disease worldwide. However, details of pathogenetic mechanisms remain unknown. Deletion of both p62/Sqstm1 and Nrf2 genes spontaneously led to the development of NASH in mice fed a normal chow and was associated with l...

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Detalles Bibliográficos
Autores principales: Akiyama, Kentaro, Warabi, Eiji, Okada, Kosuke, Yanagawa, Toru, Ishii, Tetsuro, Kose, Katsumi, Tokushige, Katsutoshi, Ishige, Kazunori, Mizokami, Yuji, Yamagata, Kenji, Onizawa, Kojiro, Ariizumi, Shun-ichi, Yamamoto, Masakazu, Shoda, Junichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2017
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955752/
https://www.ncbi.nlm.nih.gov/pubmed/29276215
http://dx.doi.org/10.1538/expanim.17-0112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955752/
https://www.ncbi.nlm.nih.gov/pubmed/29276215
http://dx.doi.org/10.1538/expanim.17-0112

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