Cargando…

How asbestos drives the tissue towards tumors: YAP activation, macrophage and mesothelial precursor recruitment, RNA editing, and somatic mutations

Chronic exposure to intraperitoneal asbestos triggered a marked response in the mesothelium well before tumor development. Macrophages, mesothelial precursor cells, cytokines, and growth factors accumulated in the peritoneal lavage. Transcriptome profiling revealed YAP/TAZ activation in inflamed mes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rehrauer, Hubert, Wu, Licun, Blum, Walter, Pecze, Lazslo, Henzi, Thomas, Serre-Beinier, Véronique, Aquino, Catherine, Vrugt, Bart, de Perrot, Marc, Schwaller, Beat, Felley-Bosco, Emanuela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955862/ https://www.ncbi.nlm.nih.gov/pubmed/29507420 http://dx.doi.org/10.1038/s41388-018-0153-z

Ejemplares similares

Establishment of immortalized murine mesothelial cells and a novel mesothelioma cell line
por: Blum, Walter, et al.
Publicado: (2015)

Overexpression or absence of calretinin in mouse primary mesothelial cells inversely affects proliferation and cell migration
por: Blum, Walter, et al.
Publicado: (2015)

Stem Cell Factor-Based Identification and Functional Properties of In Vitro-Selected Subpopulations of Malignant Mesothelioma Cells
por: Blum, Walter, et al.
Publicado: (2017)

Absence of calretinin protein expression in malignant mesotheliomas from asbestos-exposed NF2(+/−) mice and mouse mesothelioma cell lines from various mouse strains
por: Blum, Walter, et al.
Publicado: (2018)

Putative cancer stem cells may be the key target to inhibit cancer cell repopulation between the intervals of chemoradiation in murine mesothelioma
por: Wu, Licun, et al.
Publicado: (2018)

Non-Coding Transcript Heterogeneity in Mesothelioma: Insights from Asbestos-Exposed Mice
por: Felley-Bosco, Emanuela, et al.
Publicado: (2018)

The phytohormone forchlorfenuron decreases viability and proliferation of malignant mesothelioma cells in vitro and in vivo
por: Blum, Walter, et al.
Publicado: (2019)

Heterogeneous RNA editing and influence of ADAR2 on mesothelioma chemoresistance and the tumor microenvironment
por: Hariharan, Ananya, et al.
Publicado: (2022)

Routes of Ca(2+) Shuttling during Ca(2+) Oscillations: FOCUS ON THE ROLE OF MITOCHONDRIAL Ca(2+) HANDLING AND CYTOSOLIC Ca(2+) BUFFERS
por: Pecze, László, et al.
Publicado: (2015)

Menthol evokes Ca(2+) signals and induces oxidative stress independently of the presence of TRPM8 (menthol) receptor in cancer cells
por: Nazıroğlu, Mustafa, et al.
Publicado: (2017)

A liquid biopsy for detecting circulating mesothelial precursor cells: A new biomarker for diagnosis and prognosis in mesothelioma
por: Duong, Bill T.V., et al.
Publicado: (2020)

Defining and targeting tumor-associated macrophages in malignant mesothelioma
por: Wu, Licun, et al.
Publicado: (2023)

Calretinin promotes invasiveness and EMT in malignant mesothelioma cells involving the activation of the FAK signaling pathway
por: Wörthmüller, Janine, et al.
Publicado: (2018)

Comparative toxicities of different forms of asbestos on rat pleural mesothelial cells.
por: Jaurand, M C, et al.
Publicado: (1983)

Antagonistic Regulation of Parvalbumin Expression and Mitochondrial Calcium Handling Capacity in Renal Epithelial Cells
por: Henzi, Thomas, et al.
Publicado: (2015)

Regulation of calretinin in malignant mesothelioma is mediated by septin 7 binding to the CALB2 promoter
por: Blum, Walter, et al.
Publicado: (2018)

Differential Effects of Lovastatin on Cisplatin Responses in Normal Human Mesothelial Cells versus Cancer Cells: Implication for Therapy
por: Shi, Yandong, et al.
Publicado: (2012)

Gene expression profiles in asbestos-exposed epithelial and mesothelial lung cell lines
por: Nymark, Penny, et al.
Publicado: (2007)

Early mesothelial cell proliferation after asbestos exposure: in vivo and in vitro studies.
por: Adamson, I Y
Publicado: (1997)

The proliferative effects of asbestos-exposed peripheral blood mononuclear cells on mesothelial cells
por: MAKI, YUHO, et al.
Publicado: (2016)

Dual preventive benefits of iron elimination by desferal in asbestos‐induced mesothelial carcinogenesis
por: Jiang, Li, et al.
Publicado: (2016)

Caveolin1 and YAP drive mechanically induced mesothelial to mesenchymal transition and fibrosis
por: Strippoli, Raffaele, et al.
Publicado: (2020)

CD74: a new prognostic factor for patients with malignant pleural mesothelioma
por: Otterstrom, C, et al.
Publicado: (2014)

The Effect of Gap Junctional Coupling on the Spatiotemporal Patterns of Ca(2+) Signals and the Harmonization of Ca(2+)-Related Cellular Responses
por: Dougoud, Michaël, et al.
Publicado: (2016)

The Pattern of RNA Editing Changes in Pleural Mesothelioma upon Epithelial-Mesenchymal Transition
por: Felley-Bosco, Emanuela, et al.
Publicado: (2023)

Dielectric changes in membrane properties and cell interiors of human mesothelial cells in vitro after crocidolite asbestos exposure.
por: Dopp, E, et al.
Publicado: (2000)

Asbestos and erionite prime and activate the NLRP3 inflammasome that stimulates autocrine cytokine release in human mesothelial cells
por: Hillegass, Jedd M, et al.
Publicado: (2013)

Ferroptosis-dependent extracellular vesicles from macrophage contribute to asbestos-induced mesothelial carcinogenesis through loading ferritin
por: Ito, Fumiya, et al.
Publicado: (2021)

Parvalbumin alters mitochondrial dynamics and affects cell morphology
por: Lichvarova, Lucia, et al.
Publicado: (2018)

The Parvalbumin Hypothesis of Autism Spectrum Disorder
por: Filice, Federica, et al.
Publicado: (2020)

Prognostic Value of EMT Gene Signature in Malignant Mesothelioma
por: Wu, Licun, et al.
Publicado: (2023)

Analysis of YAP1 and TAZ expression by immunohistochemical staining in malignant mesothelioma and reactive mesothelial cells
por: Takehara, Yusuke, et al.
Publicado: (2018)

Analysis of YAP1 and TAZ expression by immunohistochemical staining in malignant mesothelioma and reactive mesothelial cells
por: Takehara, Yusuke, et al.
Publicado: (2018)

Crocidolite asbestos induces apoptosis of pleural mesothelial cells: role of reactive oxygen species and poly(ADP-ribosyl) polymerase.
por: Broaddus, V C, et al.
Publicado: (1997)

Synthetic Secoisolariciresinol Diglucoside (LGM2605) Prevents Asbestos-Induced Inflammation and Genotoxic Cell Damage in Human Mesothelial Cells
por: Pietrofesa, Ralph A., et al.
Publicado: (2022)

Targeting breast cancer cells by MRS1477, a positive allosteric modulator of TRPV1 channels
por: Nazıroğlu, Mustafa, et al.
Publicado: (2017)

Forchlorfenuron and Novel Analogs Cause Cytotoxic Effects in Untreated and Cisplatin-Resistant Malignant Mesothelioma-Derived Cells
por: Henzi, Thomas, et al.
Publicado: (2022)

Live-Cell Mesothelioma Biobank to Explore Mechanisms of Tumor Progression
por: Oehl, Kathrin, et al.
Publicado: (2018)

Small RNA-Seq Transcriptome Profiling of Mesothelial and Mesothelioma Cell Lines Revealed microRNA Dysregulation after Exposure to Asbestos-like Fibers
por: Filetti, Veronica, et al.
Publicado: (2023)

GAS5 long non-coding RNA in malignant pleural mesothelioma
por: Renganathan, Arun, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_dhffk46s0uckn9cd8p9kpsp4rs