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EZH2 regulates neuroblastoma cell differentiation via NTRK1 promoter epigenetic modifications
The polycomb repressor complex 2 molecule EZH2 is now known to play a role in essential cellular processes, namely, cell fate decisions, cell cycle regulation, senescence, cell differentiation, and cancer development/progression. EZH2 inhibitors have recently been developed; however, their effective...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955864/ https://www.ncbi.nlm.nih.gov/pubmed/29507419 http://dx.doi.org/10.1038/s41388-018-0133-3 |