EZH2 regulates neuroblastoma cell differentiation via NTRK1 promoter epigenetic modifications

The polycomb repressor complex 2 molecule EZH2 is now known to play a role in essential cellular processes, namely, cell fate decisions, cell cycle regulation, senescence, cell differentiation, and cancer development/progression. EZH2 inhibitors have recently been developed; however, their effective...

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Detalles Bibliográficos
Autores principales: Li, Zhenghao, Takenobu, Hisanori, Setyawati, Amallia Nuggetsiana, Akita, Nobuhiro, Haruta, Masayuki, Satoh, Shunpei, Shinno, Yoshitaka, Chikaraishi, Koji, Mukae, Kyosuke, Akter, Jesmin, Sugino, Ryuichi P., Nakazawa, Atsuko, Nakagawara, Akira, Aburatani, Hiroyuki, Ohira, Miki, Kamijo, Takehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955864/
https://www.ncbi.nlm.nih.gov/pubmed/29507419
http://dx.doi.org/10.1038/s41388-018-0133-3

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