Heterologous mammalian Akt disrupts plasma membrane homeostasis by taking over TORC2 signaling in Saccharomyces cerevisiae

The Akt protein kinase is the main transducer of phosphatidylinositol-3,4,5-trisphosphate (PtdIns3,4,5P(3)) signaling in higher eukaryotes, controlling cell growth, motility, proliferation and survival. By co-expression of mammalian class I phosphatidylinositol 3-kinase (PI3K) and Akt in the Sacchar...

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Detalles Bibliográficos
Autores principales: Rodríguez-Escudero, Isabel, Fernández-Acero, Teresa, Cid, Víctor J., Molina, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955888/
https://www.ncbi.nlm.nih.gov/pubmed/29769614
http://dx.doi.org/10.1038/s41598-018-25717-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955888/
https://www.ncbi.nlm.nih.gov/pubmed/29769614
http://dx.doi.org/10.1038/s41598-018-25717-w

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