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Computational identification and validation of alternative splicing in ZSF1 rat RNA-seq data, a preclinical model for type 2 diabetic nephropathy

Obese ZSF1 rats exhibit spontaneous time-dependent diabetic nephropathy and are considered to be a highly relevant animal model of progressive human diabetic kidney disease. We previously identified gene expression changes between disease and control animals across six time points from 12 to 41 week...

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Detalles Bibliográficos
Autores principales: Zhang, Chi, Dower, Ken, Zhang, Baohong, Martinez, Robert V., Lin, Lih-Ling, Zhao, Shanrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955895/
https://www.ncbi.nlm.nih.gov/pubmed/29769602
http://dx.doi.org/10.1038/s41598-018-26035-x