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Computational identification and validation of alternative splicing in ZSF1 rat RNA-seq data, a preclinical model for type 2 diabetic nephropathy
Obese ZSF1 rats exhibit spontaneous time-dependent diabetic nephropathy and are considered to be a highly relevant animal model of progressive human diabetic kidney disease. We previously identified gene expression changes between disease and control animals across six time points from 12 to 41 week...
Autores principales: | Zhang, Chi, Dower, Ken, Zhang, Baohong, Martinez, Robert V., Lin, Lih-Ling, Zhao, Shanrong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955895/ https://www.ncbi.nlm.nih.gov/pubmed/29769602 http://dx.doi.org/10.1038/s41598-018-26035-x |
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