Deubiquitinase function of A20 maintains and repairs endothelial barrier after lung vascular injury

Vascular endothelial cadherin (VE-cad) expression at endothelial adherens junctions (AJs) regulates vascular homeostasis. Here we show that endothelial A20 is required for VE-cad expression at AJs to maintain and repair the injured endothelial barrier. In endothelial cell (EC)-restricted Tnfaip3 (A2...

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Detalles Bibliográficos
Autores principales: Soni, Dheeraj, Wang, Dong-Mei, Regmi, Sushil C., Mittal, Manish, Vogel, Stephen M., Schlüter, Dirk, Tiruppathi, Chinnaswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955943/
https://www.ncbi.nlm.nih.gov/pubmed/29796309
http://dx.doi.org/10.1038/s41420-018-0056-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955943/
https://www.ncbi.nlm.nih.gov/pubmed/29796309
http://dx.doi.org/10.1038/s41420-018-0056-3

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