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Deubiquitinase function of A20 maintains and repairs endothelial barrier after lung vascular injury
Vascular endothelial cadherin (VE-cad) expression at endothelial adherens junctions (AJs) regulates vascular homeostasis. Here we show that endothelial A20 is required for VE-cad expression at AJs to maintain and repair the injured endothelial barrier. In endothelial cell (EC)-restricted Tnfaip3 (A2...
Autores principales: | Soni, Dheeraj, Wang, Dong-Mei, Regmi, Sushil C., Mittal, Manish, Vogel, Stephen M., Schlüter, Dirk, Tiruppathi, Chinnaswamy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955943/ https://www.ncbi.nlm.nih.gov/pubmed/29796309 http://dx.doi.org/10.1038/s41420-018-0056-3 |
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