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Integrated analysis of hepatic mRNA and miRNA profiles identified molecular networks and potential biomarkers of NAFLD

To enhance our understanding of molecular mechanisms and mine novel biomarkers of non-alcoholic fatty liver disease (NAFLD), RNA sequencing was performed to gain hepatic expression profiles of mRNAs and miRNAs in NAFLD and normal rats. Using DESeq with thresholds of a two-fold change and a false dis...

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Detalles Bibliográficos
Autores principales: Zhu, Mingzhe, Wang, Qianlei, Zhou, Wenjun, Liu, Tao, Yang, Lili, Zheng, Peiyong, Zhang, Li, Ji, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955949/
https://www.ncbi.nlm.nih.gov/pubmed/29769539
http://dx.doi.org/10.1038/s41598-018-25743-8