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Enantioselective reduction of sulfur-containing cyclic imines through biocatalysis

The 3-thiazolidine ring represents an important structural motif in life sciences molecules. However, up to now reduction of 3-thiazolines as an attractive approach failed by means of nearly all chemical reduction technologies for imines. Thus, the development of an efficient general and enantiosele...

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Detalles Bibliográficos
Autores principales: Zumbrägel, Nadine, Merten, Christian, Huber, Stefan M., Gröger, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955971/
https://www.ncbi.nlm.nih.gov/pubmed/29769523
http://dx.doi.org/10.1038/s41467-018-03841-5