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A cell-penetrating artificial metalloenzyme regulates a gene switch in a designer mammalian cell

Complementing enzymes in their native environment with either homogeneous or heterogeneous catalysts is challenging due to the sea of functionalities present within a cell. To supplement these efforts, artificial metalloenzymes are drawing attention as they combine attractive features of both homoge...

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Detalles Bibliográficos
Autores principales: Okamoto, Yasunori, Kojima, Ryosuke, Schwizer, Fabian, Bartolami, Eline, Heinisch, Tillmann, Matile, Stefan, Fussenegger, Martin, Ward, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955986/
https://www.ncbi.nlm.nih.gov/pubmed/29769518
http://dx.doi.org/10.1038/s41467-018-04440-0