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AID/APOBEC-like cytidine deaminases are ancient innate immune mediators in invertebrates

In the course of both innate and adaptive immunity, cytidine deaminases within the activation induced cytidine deaminase (AID)/apolipoprotein B editing complex (APOBEC) family modulate immune responses by mutating specific nucleic acid sequences of hosts and pathogens. The evolutionary emergence of...

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Detalles Bibliográficos
Autores principales: Liu, Mei-Chen, Liao, Wen-Yun, Buckley, Katherine M., Yang, Shu Yuan, Rast, Jonathan P., Fugmann, Sebastian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956068/
https://www.ncbi.nlm.nih.gov/pubmed/29769532
http://dx.doi.org/10.1038/s41467-018-04273-x