Cargando…

Optical functionalization of human Class A orphan G-protein-coupled receptors

G-protein-coupled receptors (GPCRs) form the largest receptor family, relay environmental stimuli to changes in cell behavior and represent prime drug targets. Many GPCRs are classified as orphan receptors because of the limited knowledge on their ligands and coupling to cellular signaling machineri...

Descripción completa

Detalles Bibliográficos
Autores principales: Morri, Maurizio, Sanchez-Romero, Inmaculada, Tichy, Alexandra-Madelaine, Kainrath, Stephanie, Gerrard, Elliot J., Hirschfeld, Priscila P., Schwarz, Jan, Janovjak, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956105/
https://www.ncbi.nlm.nih.gov/pubmed/29769519
http://dx.doi.org/10.1038/s41467-018-04342-1