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Optical functionalization of human Class A orphan G-protein-coupled receptors
G-protein-coupled receptors (GPCRs) form the largest receptor family, relay environmental stimuli to changes in cell behavior and represent prime drug targets. Many GPCRs are classified as orphan receptors because of the limited knowledge on their ligands and coupling to cellular signaling machineri...
Autores principales: | Morri, Maurizio, Sanchez-Romero, Inmaculada, Tichy, Alexandra-Madelaine, Kainrath, Stephanie, Gerrard, Elliot J., Hirschfeld, Priscila P., Schwarz, Jan, Janovjak, Harald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956105/ https://www.ncbi.nlm.nih.gov/pubmed/29769519 http://dx.doi.org/10.1038/s41467-018-04342-1 |
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