Optimization to detect TP53 mutations in circulating cell-free tumor DNA from patients with serous epithelial ovarian cancer

OBJECTIVE: Circulating cell-free tumor DNA (cfDNA) is the DNA released by apoptotic and necrotic cells of the primary tumor into the blood during the period of tumor development. The cfDNA reflects the genetic and epigenetic alterations of the original tumor. TP53 mutations are a defining feature of...

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Detalles Bibliográficos
Autores principales: Park, Yu Ran, Kim, Yong-Man, Lee, Shin Wha, Lee, Ha Young, Lee, Gun Eui, Lee, Jong-Eun, Kim, Young-Tak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Obstetrics and Gynecology; Korean Society of Contraception and Reproductive Health; Korean Society of Gynecologic Endocrinology; Korean Society of Gynecologic Endoscopy and Minimal Invasive Surgery; Korean Society of Maternal Fetal Medicine; Korean Society of Ultrasound in Obstetrics and Gynecology; Korean Urogynecologic Society 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956115/
https://www.ncbi.nlm.nih.gov/pubmed/29780774
http://dx.doi.org/10.5468/ogs.2018.61.3.328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956115/
https://www.ncbi.nlm.nih.gov/pubmed/29780774
http://dx.doi.org/10.5468/ogs.2018.61.3.328

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