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Is there a role for glucocorticoid receptor beta in asthma?
Glucocorticoids (GCs) are routinely used as anti-inflammatory drugs in the treatment of asthma. They act through binding to glucocorticoid receptor α (GRα), which represses numerous genes encoding pro-inflammatory mediators. A hormone binding deficient GR isoform named GRβ has been isolated in human...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC59562/ https://www.ncbi.nlm.nih.gov/pubmed/11686858 http://dx.doi.org/10.1186/rr31 |