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Differential susceptibility of Dectin-1 isoforms to functional inactivation by neutrophil and fungal proteases

Patients with cystic fibrosis (CF) experience chronic or recurrent bacterial and fungal lung infections. Many patients with CF cannot effectively clear Aspergillus from their lungs. This may result in IgE sensitization and the development of allergic bronchopulmonary aspergillosis, or invasive infec...

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Detalles Bibliográficos
Autores principales: Griffiths, James S., Thompson, Aiysha, Stott, Matthew, Benny, Ankita, Lewis, Natalie A., Taylor, Philip R., Forton, Julian, Herrick, Sarah, Orr, Selinda J., McGreal, Eamon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956239/
https://www.ncbi.nlm.nih.gov/pubmed/29401615
http://dx.doi.org/10.1096/fj.201701145R