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Oxidized phospholipids and lipoprotein-associated phospholipase A(2) as important determinants of Lp(a) functionality and pathophysiological role
Lipoprotein(a) [Lp(a)] is composed of a low density lipoprotein (LDL)-like particle to which apolipoprotein (a) [apo(a)] is linked by a single disulfide bridge. Lp(a) is considered a causal risk factor for ischemic cardiovascular disease (CVD) and calcific aortic valve stenosis (CAVS). The evidence...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Editorial Department of Journal of Biomedical Research
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956253/ https://www.ncbi.nlm.nih.gov/pubmed/27346583 http://dx.doi.org/10.7555/JBR.31.20160009 |