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Oxidized phospholipids and lipoprotein-associated phospholipase A(2) as important determinants of Lp(a) functionality and pathophysiological role

Lipoprotein(a) [Lp(a)] is composed of a low density lipoprotein (LDL)-like particle to which apolipoprotein (a) [apo(a)] is linked by a single disulfide bridge. Lp(a) is considered a causal risk factor for ischemic cardiovascular disease (CVD) and calcific aortic valve stenosis (CAVS). The evidence...

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Detalles Bibliográficos
Autor principal:	Tselepis, Alexandros D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editorial Department of Journal of Biomedical Research 2018
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956253/ https://www.ncbi.nlm.nih.gov/pubmed/27346583 http://dx.doi.org/10.7555/JBR.31.20160009

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