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Hydrogen Bonding in Human P450-Substrate Interactions: A Major Contribution to Binding Affinity
The importance of hydrogen bonding, a relatively strong intermolecular force of attraction between molecules in biological systems, is discussed in the respect of P450 substrate affinity towards one or more of the human P450 enzymes that are generally associated with drug and other xenobiotic metabo...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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TheScientificWorldJOURNAL
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956502/ https://www.ncbi.nlm.nih.gov/pubmed/15632987 http://dx.doi.org/10.1100/tsw.2004.210 |