Cargando…

Contributions of the RhoA guanine nucleotide exchange factor Net1 to polyoma middle T antigen-mediated mammary gland tumorigenesis and metastasis

BACKGROUND: The RhoA activating protein Net1 contributes to breast cancer cell proliferation, motility, and invasion in vitro, yet little is known about its roles in mammary gland tumorigenesis and metastasis. METHODS: Net1 knockout (KO) mice were bred to mice with mammary gland specific expression...

Descripción completa

Detalles Bibliográficos
Autores principales: Zuo, Yan, Ulu, Arzu, Chang, Jeffrey T., Frost, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956559/
https://www.ncbi.nlm.nih.gov/pubmed/29769144
http://dx.doi.org/10.1186/s13058-018-0966-2