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Valproate-induced hyperammonemia - uncovering an underlying inherited metabolic disorder: a case report

BACKGROUND: Sodium valproate is a commonly used anticonvulsant. It is widely recognized that valproate can cause hyperammonemia, particularly in people with underlying liver disease. Patients with urea cycle disorders are genetically predisposed to this adverse event and can develop severe hyperammo...

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Detalles Bibliográficos
Autores principales: Mehta, Shaine, Tayabali, Sarrah, Lachmann, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956736/
https://www.ncbi.nlm.nih.gov/pubmed/29769109
http://dx.doi.org/10.1186/s13256-018-1666-3