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Inhibition of the Hedgehog Signaling Pathway Depresses the Cigarette Smoke-Induced Malignant Transformation of 16HBE Cells on a Microfluidic Chip

BACKGROUND: The hedgehog signaling system (HHS) plays an important role in the regulation of cell proliferation and differentiation during the embryonic phases. However, little is known about the involvement of HHS in the malignant transformation of cells. This study aimed to detect the role of HHS...

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Detalles Bibliográficos
Autores principales: Qin, Yong-Xin, Yang, Zhi-Hui, Du, Xiao-Hui, Zhao, Hui, Liu, Yuan-Bin, Guo, Zhe, Wang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956770/
https://www.ncbi.nlm.nih.gov/pubmed/29722338
http://dx.doi.org/10.4103/0366-6999.231525