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Functional insights from proteome-wide structural modeling of Treponema pallidum subspecies pallidum, the causative agent of syphilis

BACKGROUND: Syphilis continues to be a major global health threat with 11 million new infections each year, and a global burden of 36 million cases. The causative agent of syphilis, Treponema pallidum subspecies pallidum, is a highly virulent bacterium, however the molecular mechanisms underlying T....

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Detalles Bibliográficos
Autores principales: Houston, Simon, Lithgow, Karen Vivien, Osbak, Kara Krista, Kenyon, Chris Richard, Cameron, Caroline E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956850/
https://www.ncbi.nlm.nih.gov/pubmed/29769048
http://dx.doi.org/10.1186/s12900-018-0086-3