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mTORC1 Is Transiently Reactivated in Injured Nerves to Promote c-Jun Elevation and Schwann Cell Dedifferentiation

Schwann cells (SCs) are endowed with a remarkable plasticity. When peripheral nerves are injured, SCs dedifferentiate and acquire new functions to coordinate nerve repair as so-called repair SCs. Subsequently, SCs redifferentiate to remyelinate regenerated axons. Given the similarities between SC de...

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Detalles Bibliográficos
Autores principales: Norrmén, Camilla, Figlia, Gianluca, Pfistner, Patrick, Pereira, Jorge A., Bachofner, Sven, Suter, Ueli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956991/
https://www.ncbi.nlm.nih.gov/pubmed/29695414
http://dx.doi.org/10.1523/JNEUROSCI.3619-17.2018