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mTORC1 Is Transiently Reactivated in Injured Nerves to Promote c-Jun Elevation and Schwann Cell Dedifferentiation
Schwann cells (SCs) are endowed with a remarkable plasticity. When peripheral nerves are injured, SCs dedifferentiate and acquire new functions to coordinate nerve repair as so-called repair SCs. Subsequently, SCs redifferentiate to remyelinate regenerated axons. Given the similarities between SC de...
Autores principales: | Norrmén, Camilla, Figlia, Gianluca, Pfistner, Patrick, Pereira, Jorge A., Bachofner, Sven, Suter, Ueli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956991/ https://www.ncbi.nlm.nih.gov/pubmed/29695414 http://dx.doi.org/10.1523/JNEUROSCI.3619-17.2018 |
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