Th2 cytokines and asthma — Interleukin-4: its role in the pathogenesis of asthma, and targeting it for asthma treatment with interleukin-4 receptor antagonists

Interleukin-4 (IL-4) mediates important pro-inflammatory functions in asthma including induction of the IgE isotype switch, expression of vascular cell adhesion molecule-1 (VCAM-1), promotion of eosinophil transmigration across endothelium, mucus secretion, and differentiation of T helper type 2 lym...

Descripción completa

Detalles Bibliográficos
Autores principales: Steinke, John W, Borish, Larry
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC59570/
https://www.ncbi.nlm.nih.gov/pubmed/11686867
http://dx.doi.org/10.1186/rr40

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC59570/
https://www.ncbi.nlm.nih.gov/pubmed/11686867
http://dx.doi.org/10.1186/rr40

Ejemplares similares