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Assigning crystallographic electron densities with free energy calculations—The case of the fluoride channel Fluc

Approximately 90% of the structures in the Protein Data Bank (PDB) were obtained by X-ray crystallography or electron microscopy. Whereas the overall quality of structure is considered high, thanks to a wide range of tools for structure validation, uncertainties may arise from density maps of small...

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Detalles Bibliográficos
Autores principales: Ariz-Extreme, Igor, Hub, Jochen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957342/
https://www.ncbi.nlm.nih.gov/pubmed/29771936
http://dx.doi.org/10.1371/journal.pone.0196751