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Constitutive metanephric mesenchyme-specific expression of interferon-gamma causes renal dysplasia by regulating Sall1 expression

Transplacental viral and parasitic infections have been shown to initiate an innate response in the mammalian embryo by increasing the expression of pro-inflammatory cytokines such as interferon-gamma (Ifng). However, the developmental consequences of an activated innate immunity and, in particular,...

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Detalles Bibliográficos
Autores principales: Yun, Kangsun, Hurwitz, Arthur A., Perantoni, Alan O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957351/
https://www.ncbi.nlm.nih.gov/pubmed/29771971
http://dx.doi.org/10.1371/journal.pone.0197356