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The adaptor molecule CD2AP in CD4 T cells modulates differentiation of follicular helper T cells during chronic LCMV infection

CD4 T cell-mediated help to CD8 T cells and B cells is a critical arm of the adaptive immune system required for control of pathogen infection. CD4 T cells express cytokines and co-stimulatory molecules that support a sustained CD8 T cell response and also enhance generation of protective antibody b...

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Detalles Bibliográficos
Autores principales: Raju, Saravanan, Kometani, Kohei, Kurosaki, Tomohiro, Shaw, Andrey S., Egawa, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957453/
https://www.ncbi.nlm.nih.gov/pubmed/29734372
http://dx.doi.org/10.1371/journal.ppat.1007053