An Improved Method for Modeling Voltage-Gated Ion Channels at Atomic Accuracy Applied to Human Ca(v) Channels

Voltage-gated ion channels (VGICs) are associated with hundreds of human diseases. To date, 3D structural models of human VGICs have not been reported. We developed a 3D structural integrity metric to rank the accuracy of all VGIC structures deposited in the PDB. The metric revealed inaccuracies in...

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Detalles Bibliográficos
Autores principales: Martinez-Ortiz, Wilnelly, Cardozo, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957504/
https://www.ncbi.nlm.nih.gov/pubmed/29719253
http://dx.doi.org/10.1016/j.celrep.2018.04.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957504/
https://www.ncbi.nlm.nih.gov/pubmed/29719253
http://dx.doi.org/10.1016/j.celrep.2018.04.024

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