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An Improved Method for Modeling Voltage-Gated Ion Channels at Atomic Accuracy Applied to Human Ca(v) Channels
Voltage-gated ion channels (VGICs) are associated with hundreds of human diseases. To date, 3D structural models of human VGICs have not been reported. We developed a 3D structural integrity metric to rank the accuracy of all VGIC structures deposited in the PDB. The metric revealed inaccuracies in...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957504/ https://www.ncbi.nlm.nih.gov/pubmed/29719253 http://dx.doi.org/10.1016/j.celrep.2018.04.024 |