Nucleus Accumbens Microcircuit Underlying D2-MSN-Driven Increase in Motivation

The nucleus accumbens (NAc) plays a central role in reinforcement and motivation. Around 95% of the NAc neurons are medium spiny neurons (MSNs), divided into those expressing dopamine receptor D1 (D1R) or dopamine receptor D2 (D2R). Optogenetic activation of D2-MSNs increased motivation, whereas inh...

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Detalles Bibliográficos
Autores principales: Soares-Cunha, Carina, Coimbra, Bárbara, Domingues, Ana Verónica, Vasconcelos, Nivaldo, Sousa, Nuno, Rodrigues, Ana João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957524/
https://www.ncbi.nlm.nih.gov/pubmed/29780881
http://dx.doi.org/10.1523/ENEURO.0386-18.2018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957524/
https://www.ncbi.nlm.nih.gov/pubmed/29780881
http://dx.doi.org/10.1523/ENEURO.0386-18.2018

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