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Nucleus Accumbens Microcircuit Underlying D2-MSN-Driven Increase in Motivation

The nucleus accumbens (NAc) plays a central role in reinforcement and motivation. Around 95% of the NAc neurons are medium spiny neurons (MSNs), divided into those expressing dopamine receptor D1 (D1R) or dopamine receptor D2 (D2R). Optogenetic activation of D2-MSNs increased motivation, whereas inh...

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Detalles Bibliográficos
Autores principales:	Soares-Cunha, Carina, Coimbra, Bárbara, Domingues, Ana Verónica, Vasconcelos, Nivaldo, Sousa, Nuno, Rodrigues, Ana João
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2018
Materias:	New Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957524/ https://www.ncbi.nlm.nih.gov/pubmed/29780881 http://dx.doi.org/10.1523/ENEURO.0386-18.2018

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