Single cell analysis of kynurenine and System L amino acid transport in T cells

The tryptophan metabolite kynurenine has critical immunomodulatory properties and can function as an aryl hydrocarbon receptor (AHR) ligand. Here we show that the ability of T cells to transport kynurenine is restricted to cells activated by the T-cell antigen receptor or proinflammatory cytokines....

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Detalles Bibliográficos
Autores principales: Sinclair, Linda V., Neyens, Damien, Ramsay, George, Taylor, Peter M., Cantrell, Doreen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958064/
https://www.ncbi.nlm.nih.gov/pubmed/29773791
http://dx.doi.org/10.1038/s41467-018-04366-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958064/
https://www.ncbi.nlm.nih.gov/pubmed/29773791
http://dx.doi.org/10.1038/s41467-018-04366-7

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