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Genome-wide haplotype association analysis of primary biliary cholangitis risk in Japanese

Primary biliary cholangitis (PBC) susceptibility loci have largely been discovered through single SNP association testing. In this study, we report genic haplotype patterns associated with PBC risk genome-wide in two Japanese cohorts. Among the 74 genic PBC risk haplotype candidates we detected with...

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Detalles Bibliográficos
Autores principales: Im, Cindy, Sapkota, Yadav, Moon, Wonjong, Kawashima, Minae, Nakamura, Minoru, Tokunaga, Katsushi, Yasui, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958065/
https://www.ncbi.nlm.nih.gov/pubmed/29773854
http://dx.doi.org/10.1038/s41598-018-26112-1