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Intraperitoneal administration of the anti-IL-23 antibody prevents the establishment of intestinal nematodes in mice

Previous studies have established that an increased Th-9 response creates a hostile environment for nematode parasites. Given that IL-23, a cytokine required for maintenance of the IL-17–secreting phenotype, has inhibitory effects on IL-9 production, we hypothesized that reducing circulating IL-23 b...

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Detalles Bibliográficos
Autores principales: Gomez-Samblas, M., Bernal, D., Bolado-Ortiz, A., Vilchez, S., Bolás-Fernández, F., Espino, A. M., Trelis, M., Osuna, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958071/
https://www.ncbi.nlm.nih.gov/pubmed/29773890
http://dx.doi.org/10.1038/s41598-018-26194-x