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Assessing the Feasibility of Neutralizing Osteopontin with Various Therapeutic Antibody Modalities

Osteopontin is a secreted glycophosphoprotein that is highly implicated in many physiological and pathological processes such as biomineralization, cell-mediated immunity, inflammation, fibrosis, cell survival, tumorigenesis and metastasis. Antibodies against osteopontin have been actively pursued a...

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Detalles Bibliográficos
Autores principales: Farrokhi, Vahid, Chabot, Jeffrey R., Neubert, Hendrik, Yang, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958109/
https://www.ncbi.nlm.nih.gov/pubmed/29773891
http://dx.doi.org/10.1038/s41598-018-26187-w