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Assessing the Feasibility of Neutralizing Osteopontin with Various Therapeutic Antibody Modalities
Osteopontin is a secreted glycophosphoprotein that is highly implicated in many physiological and pathological processes such as biomineralization, cell-mediated immunity, inflammation, fibrosis, cell survival, tumorigenesis and metastasis. Antibodies against osteopontin have been actively pursued a...
Autores principales: | Farrokhi, Vahid, Chabot, Jeffrey R., Neubert, Hendrik, Yang, Zhiyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958109/ https://www.ncbi.nlm.nih.gov/pubmed/29773891 http://dx.doi.org/10.1038/s41598-018-26187-w |
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