IgG-single-chain TRAIL fusion proteins for tumour therapy

Single-chain formats of TNF-related apoptosis inducing ligand (scTRAIL) can serve as effector components of tumour-associated antigen-targeted as well as non-targeted fusion proteins, being characterized by high tumour cell-specific induction of apoptosis through death receptor activation. We studie...

Descripción completa

Detalles Bibliográficos
Autores principales: Siegemund, Martin, Schneider, Felix, Hutt, Meike, Seifert, Oliver, Müller, Ines, Kulms, Dagmar, Pfizenmaier, Klaus, Kontermann, Roland E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958125/
https://www.ncbi.nlm.nih.gov/pubmed/29773864
http://dx.doi.org/10.1038/s41598-018-24450-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958125/
https://www.ncbi.nlm.nih.gov/pubmed/29773864
http://dx.doi.org/10.1038/s41598-018-24450-8

Ejemplares similares