Cardiac pacemaker channel (HCN4) inhibition and atrial arrhythmogenesis after releasing cardiac sympathetic activation

Clinical trials and studies with ivabradine implicate cardiac pacemaker channels (HCN4) in the pathogenesis of atrial arrhythmias. Because acute changes in cardiac autonomic tone predispose to atrial arrhythmias, we studied humans in whom profound cardiac sympathetic activation was rapidly relieved...

Descripción completa

Detalles Bibliográficos
Autores principales: Chobanyan-Jürgens, Kristine, Heusser, Karsten, Duncker, David, Veltmann, Christian, May, Marcus, Mehling, Heidrun, Luft, Friedrich C., Schröder, Christoph, Jordan, Jens, Tank, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958126/
https://www.ncbi.nlm.nih.gov/pubmed/29773827
http://dx.doi.org/10.1038/s41598-018-26099-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958126/
https://www.ncbi.nlm.nih.gov/pubmed/29773827
http://dx.doi.org/10.1038/s41598-018-26099-9

Ejemplares similares