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Super-resolution imaging reveals the sub-diffraction phenotype of Zellweger Syndrome ghosts and wild-type peroxisomes

Peroxisomes are ubiquitous cell organelles involved in many metabolic and signaling functions. Their assembly requires peroxins, encoded by PEX genes. Mutations in PEX genes are the cause of Zellweger Syndrome spectrum (ZSS), a heterogeneous group of peroxisomal biogenesis disorders (PBD). The size...

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Detalles Bibliográficos
Autores principales: Soliman, Kareem, Göttfert, Fabian, Rosewich, Hendrik, Thoms, Sven, Gärtner, Jutta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958128/
https://www.ncbi.nlm.nih.gov/pubmed/29773809
http://dx.doi.org/10.1038/s41598-018-24119-2