Sequential immunizations with a panel of HIV-1 Env virus-like particles coach immune system to make broadly neutralizing antibodies

Broadly neutralizing antibodies (bnAbs) are correlated with passive HIV/SHIV protection and are desirable components of a HIV protective immunity. In the current study, we have designed a sequential-immunization strategy with a panel of envelope glycoprotein (Env)-enriched virus-like particles (VLPs...

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Detalles Bibliográficos
Autores principales: Mohan, Teena, Berman, Zachary, Kang, Sang-Moo, Wang, Bao-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958130/
https://www.ncbi.nlm.nih.gov/pubmed/29773829
http://dx.doi.org/10.1038/s41598-018-25960-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958130/
https://www.ncbi.nlm.nih.gov/pubmed/29773829
http://dx.doi.org/10.1038/s41598-018-25960-1

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