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Calreticulin and integrin alpha dissociation induces anti-inflammatory programming in animal models of inflammatory bowel disease

Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn’s disease, is a chronic intestinal inflammatory condition initiated by integrins-mediated leukocyte adhesion to the activated colonic microvascular endothelium. Calreticulin (CRT), a calcium-binding chaperone, is known as a par...

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Detalles Bibliográficos
Autores principales: Ohkuro, Masayoshi, Kim, Jun-Dal, Kuboi, Yoshikazu, Hayashi, Yuki, Mizukami, Hayase, Kobayashi-Kuramochi, Hiroko, Muramoto, Kenzo, Shirato, Manabu, Michikawa-Tanaka, Fumiko, Moriya, Jun, Kozaki, Teruya, Takase, Kazuma, Chiba, Kenichi, Agarwala, Kishan Lal, Kimura, Takayuki, Kotake, Makoto, Kawahara, Tetsuya, Yoneda, Naoki, Hirota, Shinsuke, Azuma, Hiroshi, Ozasa-Komura, Nobuko, Ohashi, Yoshiaki, Muratani, Masafumi, Kimura, Keiji, Hishinuma, Ieharu, Fukamizu, Akiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958137/
https://www.ncbi.nlm.nih.gov/pubmed/29773794
http://dx.doi.org/10.1038/s41467-018-04420-4