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Probenecid Disrupts a Novel Pannexin 1-Collapsin Response Mediator Protein 2 Interaction and Increases Microtubule Stability

Neurite formation relies on finely-tuned control of the cytoskeleton. Here we identified a novel protein-protein interaction between the ion and metabolite channel protein Pannexin 1 (Panx1) and collapsin response mediator protein 2 (Crmp2), a positive regulator of microtubule polymerization and sta...

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Detalles Bibliográficos
Autores principales: Xu, Xiaoxue, Wicki-Stordeur, Leigh E., Sanchez-Arias, Juan C., Liu, Mei, Weaver, Maria S., Choi, Catherine S. W., Swayne, Leigh A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958195/
https://www.ncbi.nlm.nih.gov/pubmed/29867357
http://dx.doi.org/10.3389/fncel.2018.00124