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β C–H di-halogenation via iterative hydrogen atom transfer

A radical relay strategy for mono- and di-halogenation (iodination, bromination, and chlorination) of sp(3) C–H bonds has been developed. This first example of β C–H di-halogenation is achieved through sequential C–H abstraction by iterative, hydrogen atom transfer (HAT). A double C–H functionalizat...

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Detalles Bibliográficos
Autores principales: Wappes, Ethan A., Vanitcha, Avassaya, Nagib, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958344/
https://www.ncbi.nlm.nih.gov/pubmed/29896392
http://dx.doi.org/10.1039/c8sc01214h