The Secretion of miR-200s by a PKCζ/ADAR2 Signaling Axis Promotes Liver Metastasis in Colorectal Cancer

Most colorectal cancer (CRC)-related deaths are due to liver metastases. PKCζ is a tumor suppressor in CRC with reduced expression in metastasis. Given the importance of microRNAs (miRNAs) in regulating cellular plasticity, we performed an unbiased screening and identified the miR-200 family as the...

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Detalles Bibliográficos
Autores principales: Shelton, Phillip M., Duran, Angeles, Nakanishi, Yuki, Reina-Campos, Miguel, Kasashima, Hiroaki, Llado, Victoria, Ma, Li, Campos, Alex, García-Olmo, Damián, García-Arranz, Mariano, García-Olmo, Dolores C., Olmedillas-López, Susana, Caceres, Javier F., Diaz-Meco, Maria T., Moscat, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958623/
https://www.ncbi.nlm.nih.gov/pubmed/29694894
http://dx.doi.org/10.1016/j.celrep.2018.03.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958623/
https://www.ncbi.nlm.nih.gov/pubmed/29694894
http://dx.doi.org/10.1016/j.celrep.2018.03.118

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